The research division of Cell Biology, Neurobiology and Biophysics within the Department of Biology at the Faculty of Science of Utrecht University is part of the Institute of Biodynamics and Biocomplexity. The division includes several research groups and is led by Prof. Dr. Anna Akhmanova, Prof. Dr. Casper Hoogenraad and Prof. Dr. Lukas Kapitein.
Cells are the fundamental building blocks of all living organisms. Our aim is to acquire novel insights into the structure and function of cells and to decipher the cellular basis for human diseases such as cancer and neurological disorders. To achieve this goal, we combine the latest methods and technologies in molecular biology, biochemistry, genetics and microscopy.
We are interested in the mechanisms underlying cytoskeletal dynamics, membrane transport and signaling pathways that underlie cell proliferation and differentiation, neuronal development and synaptic plasticity. We investigate cellular processes at a broad range of levels, from single molecules and protein networks to cells, tissues, and whole organisms.
The main research topics within the division are cellular organization and dynamics, molecular neuroscience, biophysics, synaptic physiology, molecular oncology and molecular targeted therapies.
TRIM46 Controls Neuronal Polarity and Axon Specification by Driving the Formation of Parallel Microtubule Arrays
Control of microtubule organization and dynamics: two ends in the limelight
Controlling organelle transport and positioning with light
Microtubule minus-end binding protein CAMSAP2 controls axon specification and dendrite development
How botox binds to neurons
A hyperactive kinesin causes the eye movement disorder CFEOM1
We are looking for talented and motivated PhD and postdoctoral candidates who are interested in cytoskeletal dynamics, intracellular transport, cellular biophysics, molecular mechanisms of synaptic plasticity, antibody technologies and their therapeutic applications.