Positions available

Postdoc positions

Postdoc position in the Farías group is available on the project “Organelle contacts in neurons”

Postdoctoral position in the Kapitein group is available on “Dissecting the impact of tau aggregation on cellular architecture using innovative light microscopy”

Farías group

In the lab of Ginny Farías, 1 postdoc position (2 years) is available.

Organelle contacts in neurons.
Cell function relies on the compartmentalization of different processes. The formation of discrete organelles ensures the segregation of incompatible processes, but at the same time they must be coordinated to ensure proper cellular function. In highly polarized cells such as neurons, this organelle coordination is much more complex because of the highly asymmetric architecture of these cells. By using biochemical and imaging approaches in neurons, this project aims to identify novel players involved in organelle contacts and elucidate their contribution to neuronal function. Experience in protein-protein interaction tools and/or proteomics data analysis is required. To apply, please send your CV and a motivation letter to Dr. Ginny Farías (g.c.fariasgaldames@uu.nl).

Kapitein group

In the lab of Lukas Kapitein, 1 postdoc position is available.

Dissecting the impact of tau aggregation on cellular architecture using innovative light microscopy

The microtubule-associated protein Tau regulates crucial aspects of the neuronal cell biology. Conversely, Tau hyperphosphorylation induces its aggregation, which results in neuronal dysfunction and is closely linked to AD pathogenesis. Yet, the cellular mechanisms through which Tau aggregates disrupt neuron function remain enigmatic. This project aims to elucidate how Tau aggregation impacts organelle positioning and overall nano-architecture in cell and tissue models for AD, using advanced optical nanoscopy techniques, including expansion microscopy. We are looking for a postdoc with experience in AD pathology and/or (neuronal) cell biology.

To apply, please send your CV and a motivation letter to Lukas Kapitein (l.kapitein@uu.nl)