Cell Biology, Neurobiology and Biophysics

Taxane-induced conformational changes in the microtubule lattice activate GEF-H1-dependent RhoA signalling

stained actin and microtubules

Taxane-induced conformational changes in the microtubule lattice activate GEF-H1-dependent RhoA signalling.

Meiring JCM, Mahapatra V, Liu R, Gravett MSC, Morren D, Saunders HAJ, Choi SR, Pelster José A, Karhanova A, Metallidou I, Moore A, Spoelstra MFM, Grigoriev IS, Giono M, … Read more

Anne Rios appointed Professor of Microscopy-Driven Human Cancer and Immunotherapy Innovation


Anne Rios has been appointed Professor of Microscopy-driven Human Cancer and Immunotherapy Innovation by Utrecht University. Her professorship reflects a long-held dream: using powerful microscope technologies to understand how treatments work and how to improve them. The research by Rios, … Read more

Centriolar cap in action

Centriolar cap proteins CP110 and CPAP control slow elongation of microtubule plus ends.

Iyer SS, Chen F, Ogunmolu FE, Moradi S, Volkov VA, van Grinsven EJ, van Hoorn C, Wu J, Andrea N, Hua S, Jiang K, Vakonakis I, Potočnjak … Read more