Anna Akhmanova and Marileen Dogterom aim to understand the basic principles of internal cell organization. This knowledge will eventually make it possible to control essential cellular processes such as cell movement and division. “If you want to manipulate cells, for…
The research group of Hoogenraad has recently developed new imaging tools to visualize and manipulate the cytoskeleton and transport components in living neurons. With the ERC grant they will focus on the changes that occur within the microtubule cytoskeleton during…
Benoit RM, Frey D, Hilbert M, Kevenaar JT, Wieser MM, Stirnimann CU, McMillan D, Ceska T, Lebon F, Jaussi R, Steinmetz MO, Schertler GFX, Hoogenraad CC, Capitani G and Kammerer RA, Structural basis for recognition of synaptic vesicle protein 2C…
van der Vaart B, van Riel WE, Doodhi H, Kevenaar JT, Katrukha EA, Gumy L, Bouchet BP, Grigoriev I, Spangler SA, Yu KL, Wulf PS, Wu J, Lansbergen G, van Battum EY, Pasterkamp RJ, Mimori-Kiyosue Y, Demmers J, Olieric N,…
Lukas Kapitein received a prestigious Starting Grant from the European Research Council. This 1.5 M€ grant is intended for excellent researchers with innovative proposals. The grant will allow Lukas Kapitein to expand the research of his lab on polarized transport…
Marijn Kuijpers, Ka Lou Yu, Eva Teuling, Anna Akhmanova, Dick Jaarsma and Casper C. Hoogenraad. The ALS8 protein VAPB interacts with the ER–Golgi recycling protein YIF1A and regulates membrane delivery into dendrite. The EMBO Journal advance online publication 04 June…
Samantha A. Spangler, Sabine K. Schmitz, Josta T. Kevenaar, Esther de Graaff, Heidi de Wit, Jeroen Demmers, Ruud F. Toonen and Casper C. Hoogenraad. Liprin-α2 promotes the presynaptic recruitment and turnover of RIM1/CASK to facilitate synaptic transmission. The Journal of…
Mohan R, Katrukha EA, Doodhi H, Smal I, Meijering E, Kapitein LC, Steinmetz MO, Akhmanova A. End-binding proteins sensitize microtubules to the action of microtubule-targeting agents. Proc Natl Acad Sci U S A. 2013 May 28;110(22):8900-5. doi: 10.1073/pnas.1300395110. Epub 2013…
Anna Akhmanova:
Cellular Dynamics
Lukas Kapitein: Biophysics
Florian Berger:
Theoretical Biophysics
Agathe Chaigne:
Cell division dynamics
Ginny Farías:
Neuronal Organelle Dynamics
Martin Harterink:
C. elegans neurobiology
Casper Hoogenraad: Molecular Neuroscience
Maarten Kole:
Axonal Signalling
Harold MacGillavry:
Synapse organization
Sabrina Oliveira:
Molecular Targeted Therapies
Ihor Smal: Image Analysis, Smart Microscopy and AI
Frederik Verweij:
Extracellular Vesicle Biology
