Category: Selected publications

TRIM46 Controls Neuronal Polarity and Axon Specification by Driving the Formation of Parallel Microtubule Arrays

Sam F.B. van Beuningen, Lena Will, Martin Harterink, Anaël Chazeau, Eljo Y. van Battum, Cátia P. Frias, Mariella A.M. Franker, Eugene A. Katrukha, Riccardo Stucchi, Karin Vocking, Ana T. Antunes, Lotte Slenders, Sofia Doulkeridou, Peter Sillevis Smitt, A.F. Maarten Altelaar, Read more “TRIM46 Controls Neuronal Polarity and Axon Specification by Driving the Formation of Parallel Microtubule Arrays”

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Control of microtubule organization and dynamics: two ends in the limelight

Akhmanova A, Steinmetz MO. Nat Rev Mol Cell Biol. 2015 Dec;16(12):711-26. doi: 10.1038/nrm4084. Review

Microtubules have fundamental roles in many essential biological processes, including cell division and intracellular transport. They assemble and disassemble from their two ends, denoted the plus … Read more “Control of microtubule organization and dynamics: two ends in the limelight”

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Controlling organelle transport and positioning with light

Optogenetic control of organelle transport and positioning. Petra van Bergeijk, Max Adrian, Casper C. Hoogenraad, Lukas C. Kapitein. Nature DOI: doi.org/10.1038/nature14086

http://www.nature.com/nature/journal/vaop/ncurrent/full/nature14128.html
http://www.nature.com/nature/journal/vaop/ncurrent/full/nature14086.html

Proper positioning of organelles by cytoskeleton-based motor proteins underlies cellular events such as signaling, polarization, and growth. … Read more “Controlling organelle transport and positioning with light”

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Microtubule minus-end binding protein CAMSAP2 controls axon specification and dendrite development

Kah Wai Yau, Sam F.B. van Beuningen, Inês Cunha-Ferreira, Bas M.C. Cloin, Eljo Y. van Battum, Lena Will, Philipp Schätzle, Roderick P. Tas, Jaap van Krugten, Eugene A. Katrukha, Kai Jiang, Phebe S. Wulf, Marina Mikhaylova, Martin Harterink, R. Jeroen Read more “Microtubule minus-end binding protein CAMSAP2 controls axon specification and dendrite development”

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How botox binds to neurons

Benoit RM, Frey D, Hilbert M, Kevenaar JT, Wieser MM, Stirnimann CU, McMillan D, Ceska T, Lebon F, Jaussi R, Steinmetz MO, Schertler GFX, Hoogenraad CC, Capitani G and Kammerer RA, Structural basis for recognition of synaptic vesicle protein 2C Read more “How botox binds to neurons”

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A hyperactive kinesin causes the eye movement disorder CFEOM1

van der Vaart B, van Riel WE, Doodhi H, Kevenaar JT, Katrukha EA, Gumy L, Bouchet BP, Grigoriev I, Spangler SA, Yu KL, Wulf PS, Wu J, Lansbergen G, van Battum EY, Pasterkamp RJ, Mimori-Kiyosue Y, Demmers J, Olieric N, Read more “A hyperactive kinesin causes the eye movement disorder CFEOM1”

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