Optogenetic control of organelle transport and positioning. Petra van Bergeijk, Max Adrian, Casper C. Hoogenraad, Lukas C. Kapitein. Nature DOI: doi.org/10.1038/nature14086
http://www.nature.com/nature/journal/vaop/ncurrent/full/nature14128.html
http://www.nature.com/nature/journal/vaop/ncurrent/full/nature14086.html
Proper positioning of organelles by cytoskeleton-based motor proteins underlies cellular events such as signaling, polarization, and growth. … Read more
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Benoit RM, Frey D, Hilbert M, Kevenaar JT, Wieser MM, Stirnimann CU, McMillan D, Ceska T, Lebon F, Jaussi R, Steinmetz MO, Schertler GFX, Hoogenraad CC, Capitani G and Kammerer RA, Structural basis for recognition of synaptic vesicle protein 2C … Read more
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Marijn Kuijpers, Ka Lou Yu, Eva Teuling, Anna Akhmanova, Dick Jaarsma and Casper C. Hoogenraad. The ALS8 protein VAPB interacts with the ER–Golgi recycling protein YIF1A and regulates membrane delivery into dendrite. The EMBO Journal advance online publication 04 June … Read more
Samantha A. Spangler, Sabine K. Schmitz, Josta T. Kevenaar, Esther de Graaff, Heidi de Wit, Jeroen Demmers, Ruud F. Toonen and Casper C. Hoogenraad. Liprin-α2 promotes the presynaptic recruitment and turnover of RIM1/CASK to facilitate synaptic transmission. The Journal of … Read more
Mohan R, Katrukha EA, Doodhi H, Smal I, Meijering E, Kapitein LC, Steinmetz MO, Akhmanova A. End-binding proteins sensitize microtubules to the action of microtubule-targeting agents. Proc Natl Acad Sci U S A. 2013 May 28;110(22):8900-5. doi: 10.1073/pnas.1300395110. Epub 2013 … Read more
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Anna Akhmanova:
Cellular Dynamics
Lukas Kapitein: Biophysics
Florian Berger:
Theoretical Biophysics
Agathe Chaigne:
Cell division dynamics
Ginny Farías:
Neuronal Organelle Dynamics
Martin Harterink:
C. elegans neurobiology
Casper Hoogenraad: Molecular Neuroscience
Maarten Kole:
Axonal Signalling
Sabrina Oliveira:
Molecular Targeted Therapies
Ihor Smal: Image Analysis, Smart Microscopy and AI
Frederik Verweij:
Extracellular Vesicle Biology
